EFFECT OF ADMINISTRATION OF CRUDE AQUEOUS LEAVE EXTRACT OF Anacardium occidentale ON ISOLATED RABBIT INTESTINE

Abstract

The effect and probable mechanism of action of an aqueous extract of Anacardium occidentale on intestinal motility of the rabbit was studied. Five (5) rabbits were used as experimental animals in the study and the standard organ bath procedure was used to monitor and record the contractions of the isolated intestine of the rabbits. The result showed strong correlation between the log concentration of the extract and the % contractility of the ileum with r= 0.879. This correlation was highly significant at p,<0.05. Also regression analysis done on these result show y=12.236x-0.2789 and was highly significant at (p<0.05). The above result suggests that aqueous extract of Anacardium occidentale increase intestinal contraction in rabbits.